von Willebrand Factor 8
Synonyms
vWF; Factor VIII-related antigen
- Tech Only CPT
- Tech Pro CPT
- PowerPath Code factor 8
- Schedule Monday to Friday
- Turn Around Time Within 1-2 business days of receipt
- Disease State Acute Myeloid Leukemia (AML) / Myeloid Sarcoma, Spindle Cell Tumors / Sarcoma Subtyping
- Methodology IHC
Specimen Requirements
Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.
Diagnostic Utility
The expression of the von Willebrand Factor gene is tissue specific and confined to endothelial cells and megakaryocytes. vWF is present in plasma, in the Weibel Pallade bodies of endothelial cells, in the alpha-granule in megakaryocytes and platelets, and it is used as a marker for vascular neoplasms and megakaryocytic differentiation.
Vendor
Dako