Urinary Cytology

Synonyms

Barbotage Urine, Bladder Urine, Bladder Wash, Catheterized Urine, Clean Catch Urine, Voided Urine.

  • Tech Only CPT 88112
  • Tech Pro CPT 88112 (2)
  • PowerPath Code NGURCY, NGURCYRF
  • Schedule Monday - Friday
  • Turn Around Time Within 2 business days of receipt
  • Disease State Bladder Cancer, Bladder Infection
  • Methodology Liquid-Based Cell Enhanced Concentrated Cytology

Organs

Bladder, Kidney, Urogential Tract

Specimen Requirements

Fresh or CytoLyt fixed specimen in sterile container. No minimum/maximum volume requirements, >10mL preferred. Small volume may limit interpretation.

Collection instructions:
Urine for cytology examination should be sent to the laboratory as soon as possible after collection · If a delay of more than 24 hours cannot be avoided, add an equal amount of CytoLyt · Include method of collection on the test requisition form: voided urine, catheterized urine, or bladder lavage. Also indicate if specimen was obtained pre- or post-cystoscopy.

Voided Urine Specimen: A mid-morning specimen is most desirable.
1. Have the patient drink several glasses of water.
2. One hour later, have patient void and save the specimen. Obtain by the "clean catch" method.
3. Repeat on successive days for higher accuracy.
4. Label specimen as "Voided Urine Specimen."

Catheterized Urine Specimen:
1. Have the patient drink several glasses of water.
2. One hour later, obtain a catheterized specimen.
3. Label specimen as "Catheterized Urine Specimen."

Kidney Urine Cytology:
1. Obtain a baseline voided urine prior to urethral catheterization.
2. Kidney urine specimens are collected in surgery.
3. Kidney pelvis washings are obtained by instilling saline solution through catheter and aspirating.
4. Washings with water are not suitable as the cells are lysed.
5. Label specimen as to method of collection.Cytomegalovirus & Polyoma (BK Virus)1. Collect as routine urine or, if from an infant, obtain as much urine as possible.

Bladder Lavage:
1. Fluid obtained by saline lavage of the bladder during cystoscopy must be fixed in an equal amount of cytology collection fluid.

Clinical Significance

Cellular morphology of cytologic specimens is interpreted to dianose inflammatory, neoplastic and non-neoplastic conditions. In addition, cytologic diagnoses is used to monitor recurrent and metastatic malignant conditions.

Required Patient Info

2 patient identifiers

Storage and Transportation

When possible, store specimen at 2°C - 8°C. Specimen may be transported at 15°C - 30°C. Do not freeze.

Cause for Rejection

Improper or inadequate patient identification, frozen specimens

Retention

Primary specimen container: 7 days from processing
ThinPrep Vial: 14 days from processing
Slide: 10 years

Comments

Available for UroVysion FISH Analysis