T-PIT

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

T-PIT is the transcription factor of functioning and silent corticotroph adenomas and is useful for the diagnosis of corticotroph adenoma and null cell adenoma. T-PIT may be included as part of a panel along with transcription factors SF-1 and Pit-1 to identify null cell adenomas (all negative).