Myeloproliferative Neoplasms/Myelodysplastic Syndromes Panel

Container Type:Bone Marrow or Peripheral Blood in Heparin or EDTA. Tissue in RPMI or sterile container with saline solution. Body Fluids in RPMI or sterile container.
Preferred Volume:Bone Marrow or Peripheral Blood: 1.0 - 5.0mL - Tissue: 1cm (greatest dimension) in 2mL of RPMI - Body Fluids: 1.0 - 5.0mL

This panel is designed to identify abnormal myeloid blast, monocyte or myeloid populations and helps to determine whether blasts are of myeloid or lymphoid origin. The inclusion of anti-CD45 in each panel allows the identification of specific subpopulations of interest, in particular the identification of small numbers of blasts in the presence of large numbers of more mature cells. Any abnormal population identified can be further characterized based on the particular immunophenotype and light scatter properties.

1. Requisition form with the patient’s name, DOB, DOC and recent treatments.
2. CBC report for Peripheral Blood.

Bone Marrow and Peripheral Blood: 48-72hrs transport at room temperature.
Tissue and Body Fluids: 24hrs. Transport refrigerated.

Specimens without 2 (two) patient identifiers. Incorrect anticoagulant or lack of anticoagulant, frozen or incorrectly stored specimens (i.e., excessive heat or cold), severely hemolyzed specimens (minimal hemolysis will be evaluated on a case-by-case basis), broken or leaking tubes, specimens received with needles affixed, submitted in fixative - no fixative is acceptable, specimen age: >72 hours for peripheral blood and >5 days for bone marrow *see note below, clotted specimens (small clots are acceptable-others evaluated on a case-by-case basis), contamination (bacterial, fungal, drug interaction, chylous, etc.), incorrectly labeled specimens or insufficient transport media for tissues and FNA’s.

*Note: Peripheral blood specimens >72-hours old are reported on a case-by-case basis and must be approved by the pathologist reviewing the case. Bone marrow specimens >5-days old are reported on a case-by-base basis and must be approved by the pathologist reviewing the case.

CellNetix does NOT accept specimens where prion diseases (CJD or other types of TSEs) are suspected. These specimens should be sent by the provider directly to the National Prion Pathology Surveillance Center at Case Western Reserve University.

1 week

These tests were developed and the performance characteristics determined by CellNetix Pathology & Laboratories. They have not been cleared or approved by the US Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This laboratory is certified under CLIA-88 and is qualified to perform high complexity clinical testing. Prognostic and predictive testing should be interpreted in the context of additional clinical and/or histopathological findings.