Microphthalmia Transcription Factor (MTF)
Synonyms
MTF
- Tech Only CPT
- Tech Pro CPT
- PowerPath Code
- Schedule Monday - Friday
- Turn Around Time Within 1-2 business days of receipt
- Disease State Melanoma
- Methodology IHC
Specimen Requirements
Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.
This is a send out test.
Diagnostic Utility
Identifies: A putative marker of melanoma and cells manifesting melanocytic differentiation. However, existing antibodies to MTF show no significantly increased sensitivity over traditional melanoma markers such as HMB45 and antibodies to MART1, and show significantly less specificity.