FOXP1

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

This is a send out test.

Identifies: A non-lineage-specific nuclear transcription factor expressed in normal mature B cells at several stages of development, and in a variety of non-Hodgkin lymphomas, but not in Hodgkin lymphomas. FOXP1 is used as part of a panel of markers in immunohistochemical distinction of germinal center-derived diffuse large B cell lymphoma (DLBCL) from non-germinal center-derived DLBCL.