CD42b

  • Tech Only CPT
  • Tech Pro CPT
  • PowerPath Code
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

Diagnostic Utility

CD42b, also known as platelet glycoprotein Ib,is a cell surface and transmembrane glycoprotein, expression of which commences somewhat later in megakaryocytic development compared to CD61. CD42b is also expressed byplatelets. A subset of cases of Bernard-Soulier syndrome involve congenital deficiency of CD42b.