Ki-1 antigen

  • Tech Only CPT 88342.TC
  • Tech Pro CPT
  • PowerPath Code CD30
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

Diagnostic Utility

CD30 is expressed by the Reed-Sternberg cells and its variants in a great majority of classical Hodgkin lymphoma. It is also expressed by anaplastic large cell lymphoma, primary cutaneous CD30-positive T-cell lymphoproliferative disorders, and a subset of diffuse large B-cell lymphoma. CD30 is positive in embryonal carcinoma and is a useful marker in germ cell tumors. Note that CD30 is also expressed by a significant subset of activated B- and T-cells (non-neoplastic).


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