CCND1-IGH FISH

Synonyms

CLL, Mantle cell lymphoma, t(11;14)(q13;q32); translocation

  • Tech Only CPT
  • Tech Pro CPT 88377
  • PowerPath Code CCND1IGHFISH
  • Schedule Monday to Friday
  • Turn Around Time 5-10 days
  • Disease State Mantle Cell Lymphoma
  • Methodology FISH

Organs

Blood / Bone marrow

Specimen Requirements

Minimum of 1 mL whole blood in a purple (EDTA) or pink top tube (EDTA);
Minimum of 1 mL of bone marrow aspirate in a purple, pink, or green (heparin) top tube.
Tissue in saline, RPMI or fresh

Clinical Significance

CCND1-IGH rearrangement detected by this FISH assay is a high-value confirmation test for conventional Mantle Cell Lymphoma (MCL).

Required Patient Info

Copy of the referring client's requisition form to accompany specimen.

Storage and Transportation

Refrigerated: 5 days; ambient (room temperature): 3 days; specimen must be received by laboratory within 7 days of collection.

Cause for Rejection

Frozen specimen; clotted or grossly hemolyzed specimens; serum; specimens without 2 patient identifiers; serum or plasma, aliquots (previously open containers); specimen that were received >7-days after collection. Fixed tissue blocks

Retention

Whole blood and bone marrow - 1 week.

LOINC Code(s)

77037-0

Vendor

LDT