- Tech Only CPT
- Tech Pro CPT
- PowerPath Code CALR ex9in
- Schedule Monday to Friday
- Turn Around Time 4-6 days
- Disease State Myeloproliferative Neoplasms
- Methodology PCR
Container Type: Lavender top tube (EDTA).
Specimen Type: Whole Blood; Bone Marrow.
Preferred Volume: 5mL Whole Blood;2 mL Bone Marrow.
Minimum Volume:3 mL Whole Blood; 1 mL Bone Marrow.
Somatic mutations in CALR gene, which encodes endoplasmic reticulum chaperone Calreticulin, were found in majority of patients with Myeloproliferative neoplasms without JAK2 mutation. Insertions or deletions in exon 9 of CALR were detected in 67% of patients with essential thrombocythemia (ET) and 88% of those with primary myelofibrosis (PMF), but rarely detected in patients with polycythemia vera. This assay was designed to detect all types of insertions and deletions in exon 9 of CALR that has been reported. .
Required Patient Info
Copy of the referring clinet's requisition form to accompany specimen.
Storage and Transportation
Refrigerated:5 daysAmbient (room temperature): 3 days
Cause for Rejection
Frozen specimen; clotted or grossly hemolyzed specimens; serum; specimens without 2 patient identifiers; serum or plasma, aliquots (previously open containers).
one week - whole blood. DNA - 2 years.