Body Cavity Fluid Cytology


Ascites, Effusion, Pelvic Washing, Pericardial Fluid, Peritoneal Washing, Pleural Fluid, Thoracentesis, Misc. Body Site Fluid

  • Tech Only CPT 88112, 88305
  • Tech Pro CPT 88112 (2), 88305 (2)
  • PowerPath Code NGBF
  • Schedule Monday - Friday
  • Turn Around Time Within 3 business days of receipt
  • Disease State Benign Conditions, Malignant Conditions, Mesothelioma, Metastatic Cancers
  • Methodology Liquid-Based Cell Enhanced Concentrated Cytology


Abdomen, Heart, Thorax, Misc. Body Sites

Specimen Requirements

Fresh or CytoLyt fixed specimen in sterile container. No minimum/maximum volume requirements, >10mL preferred. Small volume may limit interpretation.

Collection instructions:
Small Volumes (50mL or less)
1. Label specimen container with the patient’s full first and last name, date of birth and source/site.
2. Immediately fix the entire specimen with at least an equal volume of 50% ethanol or CytoLyt®
3. Tighten the cap and mix the contents thoroughly.
4. Indicate the type of preservative added on the requisition.

Large Volumes (greater than 50 mL)
1. Submit a minimum of 200 ml; however, 500 ml to 1000 ml is preferred.
2. Label specimen container with the patient’s full first and last name, date of birth and source/site.

Clinical Significance

Cellular morphology of cytologic specimens is interpreted to diagnose inflammatory, neoplastic and non-neoplastic conditions. In addition, cytologic diagnoses is used to monitor recurrent and metastatic malignant conditions.

Required Patient Info

2 patient identifiers

Storage and Transportation

When possible, store specimen at 2°C - 8°C, particularly for unfixed specimens. Specimen may be transported at 15°C - 30°C. Do not freeze.

Cause for Rejection

Improper or inadequate patient identification; frozen specimens.


Primary specimen container: 7 days from processing
Secondary ThinPrep vial: 14 days from processing
Slide: 10 years


If flow cytometry is indicated, fresh or RPMI fixed specimen is required.