Epithelial specific Antigen; Epithelial glycoprotein; pCAM

  • Tech Only CPT 88342.TC
  • Tech Pro CPT
  • PowerPath Code BER
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

Diagnostic Utility

Ber-EP4 identifies pCAM, an epithelial glycoprotein, that is present in most epithelial cells except most squamous cells, hepatocytes, proximal rental tubular cells, gastric parietal cells, and myepithelial cells. It is useful in the distinction of metastatic adenocarcinoma from mesothelioma (usually negative), It is best to be used in a panel with MOC-31 and Bg8, among others.