Alpha-fetoprotein

Synonyms

AFP

  • Tech Only CPT 88342.TC
  • Tech Pro CPT
  • PowerPath Code AFP
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

Diagnostic Utility

AFP is expressed in fetal livers and in some cases of hepatocellular carcinoma, and may be included in a panel of antibodies for the latter diagnosis, including Arginase-1, HepPar1, polyclonal CEA, etc. It may also be used in the setting germ cell tumors for the identification of yolk sac tumors, though newer markers, such as SALL4, OCT3/4, and Glypican 3 may be a better choice than AFP.

Vendor

Cell Marque