The lung cancer panel is a validated genomic profile that includes 13 genes with compelling clinical and biological evidence as biomarkers to predict drug responses. The genes in our panel are connected with approved drugs in standard care or for off-label drugs in clinical trials.
Genetic profiling of these genes is useful for assessing prognosis and guiding treatment of individuals with lung cancer. SymGene Focus can also be used to help determine clinical trial eligibility for patients with alterations in genes not amenable to current FDA-approved targeted therapies.
• Designed for tumor profiling of primary or metastatic lung cancer.
• Assesses all coding exons of each gene for substitutions, insertions and deletions of less than 50 bp, and copy number variants (gene amplifications or homozygous loss).
• RET translocations/fusions are included, as well as ALK / ROS1 FISH and PD-L1 IHC.
• This test is performed to evaluate for somatic mutations within tumor samples; does not assess for germline alterations within the genes listed.
ALK ARAF BRAF EGFR ERBB2 KRAS MAP2K1 MET MTOR NRAS RET ROS1 TP53
Healthcare providers have several options for ordering Sygmene for their patients including LabDOX, fax, and phone. Healthcare providers must first complete a test requisition form to start the process. Turn around time is 7-10 days from the time a specimen is received.