The breast cancer panel is a validated genomic profile that includes 8 genes with compelling clinical and biological evidence as biomarkers to predict drug responses. The genes in our panel are connected with approved drugs in standard care or for off-label drugs in clinical trials.
Genetic profiling of these genes is useful for assessing prognosis and guiding treatment of individuals with breast cancer. SymGene Breast can also be used to help determine clinical trial eligibility for patients with alterations in genes not amenable to current FDA-approved targeted therapies.
• Designed for tumor profiling of primary or metastatic breast cancer.
• Assesses all coding exons of each gene for substitutions, insertions and deletions of less than 50 bp, and copy number variants (gene amplifications or homozygous loss).
• This test is performed to evaluate for somatic mutations within tumor samples; does not assess for germline alterations within the genes listed.
AKT1 BRCA1 BRAC2 CDKN2A ERBB2 ESR1 PIK3CA PTEN
Healthcare providers with several options for ordering SymGene for their patients including LabDOX, fax, and phone. Healthcare providers must first complete a test requisition form to start the process. Turn around time is 7-10 days from the time a specimen is received.