HHV8 (Herpes virus 8, human)

Synonyms

HHV-8, Human herpes virus type 8 latent nuclear antigen-1, KSHV

  • Tech Only CPT 88342.TC
  • Tech Pro CPT
  • PowerPath Code HHV
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Disease State HIV-Associated Lymphoma, Identification of Organisms, Post-Transplant Lymphoproliferative Disorders
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

Diagnostic Utility

Identifies: HHV8 latent nuclear antigen, or LANA, a nuclear protein expressed by cells infected with HHV8. It is expressed in both Kaposi's sarcoma as well as HHV8-associated lymphoproliferative disorders, including primary effusion lymphomas and multicentric Castleman's disease.

Vendor

Novocastra