Kappa Light Chain

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

It is used to identify kappa light chain expressed in the cytoplasm of plasma cells and plasmacytoid lymphocytes, which in turn may help in determining kappa or lambda light chain restriction, a surrogate for clonality.