TP53 FISH

Synonyms

Mantle cell lymphoma, t(11;14)(q13;q32); translocation

  • Tech Only CPT
  • Tech Pro CPT 88377
  • PowerPath Code TP53FISH
  • Schedule Monday to Friday
  • Turn Around Time 5-10 days
  • Disease State Mantle Cell Lymphoma
  • Methodology FISH

Organs

Blood/Bone Marrow

Specimen Requirements

Minimum of 1 mL whole blood in a purple (EDTA) or pink top tube (EDTA); minimum of 1 mL of bone marrow aspirate in a purple, pink, or green (heparin) top tube. Tissue in saline, RPMI or fresh

Clinical Significance

TP53 gene or 17p deletion are among the strongest adverse biologic features in Mantle Cell Lymphoma (MCL).

Required Patient Info

Copy of the referring client's requisition form to accompany specimen.

Storage and Transportation

Refrigerated: 5 days; ambient (room temperature): 3 days; specimen must be received by laboratory within 7-days of collection.

Cause for Rejection

Frozen specimen; clotted or grossly hemolyzed specimens; serum; specimens without 2 patient identifiers; serum or plasma, aliquots (previously open containers); specimen that were received >7-days after collection. Fixed tissue blocks

Retention

Whole blood and bone marrow - 1 week.

LOINC Code(s)

96970-9

Vendor

LDT