TP53 FISH
Mantle cell lymphoma, t(11;14)(q13;q32); translocation
- Tech Only CPT
- Tech Pro CPT 88377
- PowerPath Code TP53FISH
- Schedule Monday to Friday
- Turn Around Time 5-10 days
- Disease State Mantle Cell Lymphoma
- Methodology FISH
Organs
Specimen Requirements
Minimum of 1 mL whole blood in a purple (EDTA) or pink top tube (EDTA); minimum of 1 mL of bone marrow aspirate in a purple, pink, or green (heparin) top tube. Tissue in saline, RPMI or fresh
Clinical Significance
TP53 gene or 17p deletion are among the strongest adverse biologic features in Mantle Cell Lymphoma (MCL).
Required Patient Info
Copy of the referring client's requisition form to accompany specimen.
Storage and Transportation
Refrigerated: 5 days; ambient (room temperature): 3 days; specimen must be received by laboratory within 7-days of collection.
Cause for Rejection
Frozen specimen; clotted or grossly hemolyzed specimens; serum; specimens without 2 patient identifiers; serum or plasma, aliquots (previously open containers); specimen that were received >7-days after collection. Fixed tissue blocks
Retention
Whole blood and bone marrow - 1 week.
LOINC Code(s)
96970-9