- Tech Only CPT
- Tech Pro CPT 88342.TC, 88342.26
- PowerPath Code BETA
- Schedule Monday - Friday
- Turn Around Time Within 1-2 business days of receipt
- Disease State Spindle Cell Tumors / Sarcoma Subtyping
- Methodology IHC
Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.
Abnormal nuclear localization of beta catenin generally indicates the presence of a mutation in WNT/APC pathway. Such mutations are characteristic of abdominal fibromatoses. High levels of nuclear beta catenin expression can also be seen in endometrial stromal tumors, synovial sarcomas, solitary fibrous tumors, and a subset of colorectal and endometrial adenocarcinoma.