Dr. Elizabeth Kehr co-authored the chapter titled “Metastatic Tumors Involving the Ovary,” in the Third Edition of Diagnostic Gynecologic and Obstetric Pathology. This chapter details the various sites of origin and addresses the many challenges encountered in diagnosing metastatic tumors to the ovary. The reported frequency of metastatic tumors in the ovary varies with the study design and country of origin, but range from 15 percent to 25 percent of all malignancies involving the ovary. Among cases that clinically or pathologically mimic a primary ovarian tumor, most originate from the endometrium, the gastrointestinal tract, the pancreas and the breast. Metastases to the ovary typically offer an overall five year survival of approximately 20 percent.
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