PMS2

Synonyms

Post meiotic segregation increased 2 gene

  • Tech Only CPT 88342.TC
  • Tech Pro CPT
  • PowerPath Code PMS
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

Diagnostic Utility

The PMS2 gene product is involved in DNA mismatch repair and interacts with MLH1 and MSH2. Mutation of the mismatch repair genes (MLH1, MSH2, PMS1 and PMS2 is found in hereditary and non-hereditary colon cancers, endometrial cancers and others cancers.

Vendor

Biocare Medical