PMS2
Synonyms
Post meiotic segregation increased 2 gene
- Tech Only CPT 88342.TC
- Tech Pro CPT
- PowerPath Code PMS
- Schedule Monday - Friday
- Turn Around Time Within 1-2 business days of receipt
- Methodology IHC
Specimen Requirements
Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.
Diagnostic Utility
The PMS2 gene product is involved in DNA mismatch repair and interacts with MLH1 and MSH2. Mutation of the mismatch repair genes (MLH1, MSH2, PMS1 and PMS2 is found in hereditary and non-hereditary colon cancers, endometrial cancers and others cancers.
Vendor
Biocare Medical