PAX-6

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

This is a send out test.

Identifies: PAX-6 is a member of the paired box protein family, and is a sensitive marker of pancreatic endocrine neoplasms. However, there is a lack of specificity as PAX-6 is also expressed by other neuroendocrine neoplasms and even some non-neuroendocrine tumors (e.g., endometrial and ovarian carcinomas).