Clusterin

  • Tech Only CPT
  • Tech Pro CPT
  • PowerPath Code
  • Schedule Monday - Friday
  • Turn Around Time Within 1-2 business days of receipt
  • Disease State Anaplastic Large Cell Lymphoma (Systemic or Cutaneous), Diffuse Large B Cell Lymphoma
  • Methodology IHC

Specimen Requirements

Formalin-fixed, paraffin embedded tissue block or cell block, or 1 unstained charged slide for each test requested plus 3-4 additional unstained slides cut at 4 microns. Adequate space on each slide for control tissue is required.

This is a send out test.

Diagnostic Utility

Identifies a heterodimeric protein associated with clearance of cell debris and apoptosis. It is expressed in diffuse large B-cell lymphomas (DLBCL), T-cell rich large B-cell lymphoma, Hodgkin lymphoma, as well as various carcinomas. Clusterin has proven to be an effective tool in the differentiation of anaplastic large cell lymphoma (ALCL) from peripheral T cell lymphoma (PTCL), NOS.Subcellular Localization: Cytoplasmic, in a granular diffuse and/or a Golgi pattern